Find support for every
step of your treatment,
including how to access VEPPANU, copay assistance, patient support services, and additional resources

RIGEL ONECARE is here to support you along your treatment journey with VEPPANU*

Patient Support Team

Case Managers

Financial and Copay Assistance

The Patient Support Team at RIGEL ONECARE is fully trained to support you and will:

  • Connect with your insurance plan and your healthcare providers to understand your coverage
  • Determine if you qualify and help you enroll in copay and financial assistance programs
  • Answer any questions you may have during your treatment with VEPPANU
  • Be ready and available Monday-Friday 8 AM to 8 PM ET to address any questions or concerns

Start here to see how RIGEL ONECARE can support you

All RIGEL ONECARE programs are subject to eligibility requirements and changes. Criteria above do not represent all criteria for each program. Must be U.S. resident or U.S. territory resident. Restrictions apply.

VEPPANU financial assistance

Eligible patients with commercial insurance pay as little as $0 per prescription fill with the VEPPANU copay assistance program.

  • Fill out and submit your information to determine if you are eligible
  • Print out the copay card and have it available when speaking with the specialty pharmacy
Sign up!

All RIGEL ONECARE programs are subject to eligibility requirements and changes. Criteria above do not represent all criteria for each program. Must be U.S. resident or U.S. territory resident. Restrictions apply.

Foundations with financial assistance

The following groups may be able to give you additional help with paying for your treatment

What is VEPPANU?

VEPPANU is a prescription medicine to treat people with estrogen receptor (ER)-positive, human epidermal growth factor receptor 2 (HER2)-negative, ESR1-mutated advanced breast cancer or breast cancer that has spread to other parts of the body (metastatic), and whose disease has progressed after at least one line of endocrine-based therapy.

Your healthcare provider will perform a test to make sure that VEPPANU is right for you.

It is not known if VEPPANU is safe and effective in children.

IMPORTANT SAFETY INFORMATION

VEPPANU can cause serious side effects, including:

  • Heart rhythm problems (QTc interval prolongation). VEPPANU can cause changes in the electrical activity of your heart and may increase your risk of abnormal heart rhythm problems, and sudden death. Your healthcare provider will check your heart with a test called an electrocardiogram (ECG) and check your blood potassium and magnesium levels before and as needed during treatment with VEPPANU. Get emergency medical help right away if you get any signs and symptoms of abnormal heart rhythm, including:
    • feeling lightheaded or faint
    • feeling that your heart is pounding or beating fast (heart palpitations)
    • shortness of breath
    • chest pain
    • dizziness

Before taking VEPPANU, tell your healthcare provider about all of your medical conditions, including if you:

  • have heart failure or heart rhythm problems, including QTc prolongation, and long QTc syndrome
  • have low blood levels of potassium or magnesium
  • are pregnant or plan to become pregnant. VEPPANU can harm your unborn baby.

    Females who are able to become pregnant:

    • Your healthcare provider may do a pregnancy test before you start treatment with VEPPANU.
    • Use effective birth control (contraception) during treatment with VEPPANU and for 2 weeks after the last dose.
    • Tell your healthcare provider right away if you become pregnant or think you may be pregnant during treatment with VEPPANU.

    Males with female partners who are able to become pregnant:

    • Use effective birth control (contraception) during treatment with VEPPANU and for 2 weeks after the last dose.
  • are breastfeeding or plan to breastfeed. It is not known if VEPPANU passes into your breast milk. Do not breastfeed during treatment with VEPPANU and for 2 weeks after the last dose.

Tell your healthcare provider about all the medicines you take, including prescription and over-the counter medicines, vitamins, and herbal supplements. VEPPANU and other medicines may affect the way each other works and may cause serious side effects.

What should I avoid while taking VEPPANU?

Avoid taking St. John’s wort, eating grapefruit, or drinking grapefruit juice during treatment with VEPPANU.

The most common side effects of VEPPANU include:

  • decreased white blood cell counts
  • increased liver function tests
  • muscle and bone pain
  • tiredness
  • decreased red blood cell counts
  • nausea
  • decreased potassium levels in your blood
  • decreased appetite
  • abnormal electrocardiogram (QT prolonged)
  • decreased platelet counts
  • constipation

Your healthcare provider may decrease your dose, temporarily stop, or completely stop treatment with VEPPANU, if you develop certain side effects.

VEPPANU may affect fertility in males and in females who are able to become pregnant. Talk to your healthcare provider if this is a concern for you.

These are not all of the possible side effects of VEPPANU. Call your doctor for medical advice about side effects. You may report side effects to FDA. Visit www.fda.gov/medwatch or call 1‑800‑FDA‑1088.

Click here for Full Prescribing Information, including Patient Information.

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Product questions or medical inquiries?

Please send any medical inquiries and report complaints or adverse events to: Rigel Medical Communications Center at 1‑800-983-1329 or producthelp@rigel.com

You may also report adverse events associated with taking our prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1‑800-FDA-1088 (1-800-332-1088).

Call 1-833-RigelOC (1-833-744-3562) Monday-Friday 8 AM to 8 PM ET to contact RIGEL ONECARE

IMPORTANT SAFETY INFORMATION

What is VEPPANU?

VEPPANU is a prescription medicine to treat people with estrogen receptor (ER)-positive, human epidermal growth factor receptor 2 (HER2)-negative, ESR1-mutated advanced breast cancer or breast cancer that has spread to other parts of the body (metastatic), and whose disease has progressed after at least one line of endocrine-based therapy.

Your healthcare provider will perform a test to make sure that VEPPANU is right for you.

It is not known if VEPPANU is safe and effective in children.

IMPORTANT SAFETY INFORMATION

VEPPANU can cause serious side effects, including:

  • Heart rhythm problems (QTc interval prolongation). VEPPANU can cause changes in the electrical activity of your heart and may increase your risk of abnormal heart rhythm problems, and sudden death. Your healthcare provider will check your heart with a test called an electrocardiogram (ECG) and check your blood potassium and magnesium levels before and as needed during treatment with VEPPANU. Get emergency medical help right away if you get any signs and symptoms of abnormal heart rhythm, including:
    • feeling lightheaded or faint
    • feeling that your heart is pounding or beating fast (heart palpitations)
    • shortness of breath
    • chest pain
    • dizziness

Before taking VEPPANU, tell your healthcare provider about all of your medical conditions, including if you:

  • have heart failure or heart rhythm problems, including QTc prolongation, and long QTc syndrome
  • have low blood levels of potassium or magnesium
  • are pregnant or plan to become pregnant. VEPPANU can harm your unborn baby.

    Females who are able to become pregnant:

    • Your healthcare provider may do a pregnancy test before you start treatment with VEPPANU.
    • Use effective birth control (contraception) during treatment with VEPPANU and for 2 weeks after the last dose.
    • Tell your healthcare provider right away if you become pregnant or think you may be pregnant during treatment with VEPPANU.

    Males with female partners who are able to become pregnant:

    • Use effective birth control (contraception) during treatment with VEPPANU and for 2 weeks after the last dose.
  • are breastfeeding or plan to breastfeed. It is not known if VEPPANU passes into your breast milk. Do not breastfeed during treatment with VEPPANU and for 2 weeks after the last dose.

Tell your healthcare provider about all the medicines you take, including prescription and over-the counter medicines, vitamins, and herbal supplements. VEPPANU and other medicines may affect the way each other works and may cause serious side effects.

What should I avoid while taking VEPPANU?

Avoid taking St. John’s wort, eating grapefruit, or drinking grapefruit juice during treatment with VEPPANU.

The most common side effects of VEPPANU include:

  • decreased white blood cell counts
  • increased liver function tests
  • muscle and bone pain
  • tiredness
  • decreased red blood cell counts
  • nausea
  • decreased potassium levels in your blood
  • decreased appetite
  • abnormal electrocardiogram (QT prolonged)
  • decreased platelet counts
  • constipation

Your healthcare provider may decrease your dose, temporarily stop, or completely stop treatment with VEPPANU, if you develop certain side effects.

VEPPANU may affect fertility in males and in females who are able to become pregnant. Talk to your healthcare provider if this is a concern for you.

These are not all of the possible side effects of VEPPANU. Call your doctor for medical advice about side effects. You may report side effects to FDA. Visit www.fda.gov/medwatch or call 1‑800‑FDA‑1088.

Click here for Full Prescribing Information, including Patient Information.